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Int
Tinnitus J. 2004;10(2):150-5.
Related Articles, Links Otorhinolaryngology Service, Specialties Center Doctor Fleming, Virgin of the Rocio University Hospital, Seville, Spain. malopez@cica.es Sequential sound therapy, which uses wide-band white noise distinguished by some unique characteristics, is applied in the treatment of tinnitus. The methodology is described, as are the differences from and similarities to tinnitus retraining therapy. We have performed sequential sound therapy in 26 patients from 2002 through part of 2003. Thirty-eight generators of sounds were adapted for use in this therapy and, of these, 34 incorporated an earphone. The results of sequential sound therapy in our 26 patients were compared with the results of tinnitus retraining therapy in 15 patients treated during the years 2000 and 2001. Satisfactory results obtained with sequential sound therapy totaled 100%, whereas only 33% of subjects treated with tinnitus retraining therapy obtained satisfactory results. In 6 patients who received sequential sound therapy, tinnitus disappeared altogether. In addition, no patient receiving sequential sound therapy has left the treatment protocol, whereas 53% of patients receiving tinnitus retraining therapy abandoned the treatment protocol. ----------------------------------------------------------------------------------------------------------------------- PMID:
15732513 [PubMed - indexed for MEDLINE] Neuroscience Research Institute, State University of New York at Old Westbury, New York 11568, USA. The use of music as a means of inducing positive emotions and subsequent relaxation has been studied extensively by researchers. A great deal of this research has centered on the use of music as a means of reducing feelings of anxiety and stress as well as aiding in the relief of numerous pathologies. The precise mechanism responsible for these mediated effects has never been truly determined. In the current report we propose that nitric oxide (NO) is the molecule chiefly responsible for these physiological and psychological relaxing effects. Furthermore this molecules importance extends beyond the mechanistic, and is required for the development of the very process that it mediates. Nitric oxide has been determined to aid in the development of the auditory system and participate in cochlear blood flow. We show that NO is additionally responsible for the induced exhibited physiological effects. We proceed to outline the precise neurochemical pathway leading to these effects. Furthermore we explore the interrelationship between the varying emotion centers within the central nervous system and explain how the introduction of music can mediate its effects via NO coupled to these complex pathways.
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